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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7c8d171ac63917387f714e8dd3c24957d9612819a77c5c45062d5fbf6d4d7ed8' 
  AND token = 'R7rjYao1kuYr2JA0rM6VJj+MsLzz7SKFPYE6TbZmG3U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}