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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '81ca4e610c8bb0aed87810000e469ad4ecd532281649f008b0377458b5c389d2' 
  AND token = '1niCQKQT9dyHo9uZ0z38PKgmE3Rim31IZzy6bj9+Wk8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}