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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed749d02e9e36047c5692f36201ef6bc31e6ce54f3e87a94baaaf1dac868648f' 
  AND token = 'QU3l4l57Ry//i4/F0l2ETJoVhcXxcQz/8D7fVGMPLSk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}