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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f4cd6a266c2045991449c6a734d0fef37066b99709eb2fad261d9370a4be703f' 
  AND token = '+EwXwCbs7W/cZiB9uoW41Zs0upY/AUeHhFh4RLdR6MQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}