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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '69122662aa4f8362ff26e6fa985404b614173cc70b6b130ecd4a75123e12d6a2' 
  AND token = 'RGYr3bdrNs0a5mtu0JnczYDV+/7lB1cIzZ6KXygvvu4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}