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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0f3c1132af3517b7e072b445ef7a6b1233f529f24ae9875b002a0d6f387017a6' 
  AND token = 'DEuZ7KTDX5qdb+huW8JBGjBMrOkc6zu0BndyyW5wCS0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}