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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6b8fa75a4229202b9a708ee816f76c6e429d0ce0e108b422eda4006298dfca7c' 
  AND token = 'XGN7yoyLq1Vr2hTwGJgbbUJdXb5APhOEYUFU752amVI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}