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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a42e2f22c6320e809d501af1f14f344b3bb13866564350df2fba0553c85ab587' 
  AND token = 'UafM4pgJX5VwaQMik80GjruybgOn1yjKa5YxqsKAwK8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}