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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '23d4e790951908dbda8deb6b8d26b4381de4f887b3f779d6cd67691b0194429a' 
  AND token = 'agF/Ts6YxuXSTe7qJPnpSjSze1EZnCeALz1668c54WE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}