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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '54df38ea1d9ede4fe552d59ffbf27236b30fe489a7c6094885efbeb5a79aac6c' 
  AND token = 'cFzPTcseDC4dirF0KqXQr+lrskdxKonDKfCzRgm1XOs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}