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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4865f5534c38b38edabb1c8951fb643d206e80228eb78a2eb4f851bb50e0e254' 
  AND token = 'WCzLjsQjdv8L5py6qCBWp001OZqa1wfWhR+54KqPg1w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00060

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}