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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f50bacd2a8621f62434b03c3218edaf50a466aa7a61297bc295b09fbe6f4fe8e' 
  AND token = 'MWpAFKeNV9mwz2eSsvn5Tv/Wu4sdC4GXsqptNbtPtM4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}