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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0b02778091b51d960c91abf4d6133fcc7fccfd0d5f567d84d7832d026855584f' 
  AND token = 'vgxft30x3nVT300xOcfLoQIRmmwKjQQxBkV/SZyjnZ0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}