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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e66646a8d50d7479e0f5783ed484d91d4ff357670eadde48564468f9a98d6b66' 
  AND token = 'La3lVpnFN0MGy+KowTD3rFagKKnMlALw0QYw5GTFYbc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}