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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '661e701744ff949e28c6d2618caf02253b5c3cda4bb6679b1cbfb84c1e61838b' 
  AND token = 'hU1lG0PC1eAnJWm7s8OefHC5M6k9plXPjBE5LM5Qsyk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}