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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3af4df34114a9aa5d53d039d2a63a01ea8ec094dd5fd617c56d3bf7fa9c7c28b' 
  AND token = 'zskSV1wUE6uuQzj5PwTaVCLyHovvxAizl4b1Ppbr8Qc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}