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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7477a42397855ce53d8d630704b13fd3bd1072735ded86da3a8037116cbb3a10' 
  AND token = '2KpeIPKp4ir6hsZAUrxZCSEetPEPafTs/gig5yt6gg8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}