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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '34443dfadde95878102f8fd88bb7b0db8248910fba8cc7f5e2b2b17e4ec2f4dd' 
  AND token = '2YndfrQxxVYBm1O7HBKO1I9CEvQA43pIAY2ixLJRJHU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}