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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de28139afad16b4fdbe1d1e404e08ec3ed11145c74355094b8c5f19d9a15a82b' 
  AND token = 'uYHTlidDQAN7vVNe30veyu/VS0XIYX1KrhS0qKD8wl4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}