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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7d81cfd3f30594f4f9799436f40f74c22c6a265544999e1273dc51afc7095a99' 
  AND token = 'sRt4yjC2fSH7RE0FhJXgoe2T7Lz+5s2MiVWVfPpH1AI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}