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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6aeaff8cbc44980869695fa761d92c4986a600b43592fcb22a769b8709f59ab3' 
  AND token = 'JtUf9gq8J8SEtOmp4tvEFzDFYVYRK5L6dkJMaJdaosM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}