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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a5f55b111d6d2333936542ae0717f10f0934b5ad6ff11d99990d100eac88a05e' 
  AND token = 'k9vxbrl1UxjlFPVoyRRlXTRz2Bp91wtSFS6Q+J5vT28=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}