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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8465a5890ed0d36d7908064d14f56f5d680f35e017200db669e87fc874790e1a' 
  AND token = 'd4YgcwBE9udwkLdXT8wwG2D1IEoGw820v1w5M/mQ/Ls=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}