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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6b3880d06ca1da525d9a953796d526d4434f7201462a44d6cb7bb57de9caf917' 
  AND token = 'VX+XtLa9BNHHzNpSOMF8InEzCGIizAAwCJ5WU2otzSs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}