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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a80eef4b17e756369a0d87f9c22005a15b4af654b333c78978c2a304a2a9bdfb' 
  AND token = 'CcMJM/drlQknmkmhN70joCKh5gWZ9QtIygBSlEY8Hhk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00058

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}