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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5f4f04d55ab61274ff0dff357f8e34bc6cab4a9be53fe28163c033188083044f' 
  AND token = 'R8lYYsfREH7Da5247uXJLaPQ9uPqH/fTQCYrwWYiiMY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}