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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1af207dad582a15b7a64e672f39e90edb2fed9a321cd2fa04f4de7ed4bd2fd78' 
  AND token = 'rXkOXIxS1PJQ2yYQa1x4EMvWbqanc9l7idVoPdp+nhE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}