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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f64e35074e61166eeb557b811725e58b320f10be0d7cb4292e42e00f4afea7e2' 
  AND token = '+4H7kRAa0uaRpZhe0aiiptRoAE5b5mPQ/mO+2dfSqXE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}