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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0d9258a1fd7fbe4465ef06b8ec308ab2ef29cff0af5d2d9d056ae59d23f494d5' 
  AND token = '7JcqVUf52TrxK4oIxob2ZIY7GRUH3oxp3FrYAgYw1jg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}