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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '31b45c1789353ddb102bdc3ab9f64e1427f06d0444d77898b09d067a08e26523' 
  AND token = 'H4BJM0ns8fOyg5uGuFHhiNflcnZKkI9GamuwMOvxeW8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}