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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e08ceb9d91bdaa420020ef7a8d7018d7d3e7ea2c5bee4a13777c75477a48913' 
  AND token = 'jW/8gSKSWRq6xH8kA/eyq4iDS+szjvbHuy7gXFnOhJA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}