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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e0c06e5e22ba04efe336a8953f71351d59d4859644c8442a24c73c7b9b0c7502' 
  AND token = 'OTmGOhwA+mKVZe69k0vK8QOAtsfTRfGCBCNvyM6EyHs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}