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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6a65005c46d8a5a810155dccf325735b45be8b1aebf54696a8d0036b1c45bc71' 
  AND token = 'o1tn2YD/JlxDCJvC3z2siI61khoLtrmbhXPyhLotYCM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}