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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '37e3f7fe4dd1e657654d16dc8a13d5e9ef9953d568680bcc1c5659b605a176ec' 
  AND token = 'k8pgdPq220gnVrt0eo0gV4Sd/L5F+ISWlVx+gsUTqZ4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}