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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e5022d2635094fd3da9f8690a5beb761d0acb49595ec9fba1eaf725398d472c5' 
  AND token = 'Z1/YP9T+6HDO1SK7ZdIugZ2v+B+HkVeNorV5RFki5II=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}