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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5a93cd695e93a5c0357a191108516e30c220e34a9d0faf5831e96986139c4e9c' 
  AND token = 'P8oJ8C4313nv2wjJ08WRm+hwGfBePgwCv6Ix2yfmBZE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}