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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd86d57f7fa347487b8a38c8c33ceeb480b2c6fe13ab85bab8473141f19d0bf1f' 
  AND token = '+a23YlGbEG9mwsYdMaL2P1hc0ptKyFTSLp/gfAsagWA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}