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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e50d92cb5a013076c03a026fb1cec6423d39d3aa8ab7ea6ab6aa1f1e2d646de4' 
  AND token = 'KXMHbyXP934kzjPMJ075CpU+V9Hv3AhZJ1+6SVcd+Uw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}