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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e4f8ab6a02c9454a0336c58282490f4151f4cdbe2d180b01a6ebe5713831c41' 
  AND token = 'KJi04Pwk4wiiGbcpOLj5dIKnaXpW57VksDf2PvFgW5M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}