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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fef3b22a25be38a93d37e9c29e78ef8a3929766534b673f0e514002ea33272fe' 
  AND token = 'EDwynn8zb0C+PCRX+b7MhA/V77Y1M2fezGWcEt7CgHE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}