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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd209984151db19049a1f69a8de8771bf23075c0d66a8f11806671a8a9dd9fbba' 
  AND token = 'gUKvzjX/M9RQjQ3+5+RsVesi9uh00+HR+cO7WFUACh0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}