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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cdf596ba8c060021a0cd74bfbc213531b0ba1a4dcc44b05fad3fa417b54bf045' 
  AND token = 'RsMy1rmfADGEAQLiJVtHF/8tQ04FbcjCpKyeiRmtd8w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}