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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '64750b5229e25083f6d11003a4aa1ac1aae7ec935b597bda1cdba886f09ca5d3' 
  AND token = 'rHZk7p2gq3rd/Zla9AH3I7Fr2coiLULz8+fv6QAP2K0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00078

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}