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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5854cad2a7e72cd35b4752fd0cb422b121d9fd9f5aafa3be8e3e319e7ddf8732' 
  AND token = 'xrlWX/5TCOF1c3QDbjEwxdDjV3E8A3mhSzIB89YlNRA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}