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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c320eb7fcb1eacd2aae355c9c26324966ead170ecfbe7862c21816f636498c81' 
  AND token = 'nVrjOR3TaOgWNx1ZwRT/jW+aL4+vfUccZ2wBhsrKxXY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}