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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ea8d863cc330c19fab73dc7bd2d19abd5a4667cf884b907b2e64cd1aff37ddec' 
  AND token = '/UTNG711c61UDFtVJiYyVFuhPw9Xz25LGri8enygx8w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}