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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '78e2a75790715c952868d3b179e9c0990e84ad2d4525ee70ddfbfbebf6d518a1' 
  AND token = 'wXoETA6arNwUl/QPbnjGNoDP6yyy57Oa29r4sldrU7I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}