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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eb318c6ca44a44577cf1192e879d85b615f0e91015c42a3b73f2d6d56c4bacc5' 
  AND token = 'b9XlEjVOzhJ2q11J/4mnnq6+4CFPayaKmmNSTfbbs4Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}