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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e5a5ff53edbff1a7ac508e53e2216af9b778f1f74110947b320b6170d3a1b6b8' 
  AND token = '0LrQWeF/abbB5koY56JvHMhsVLOih18DQffnLP0wEQ8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}