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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6208efd9067c1c2ba358c2eca41e85c1c3c5d29877009908843b1c53e19d966f' 
  AND token = 'PMkAjINFV2qRSYat1oMu/gGID/flIJ9S/nfg52/En6U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}